Sergey Deyev Selected Research

Neoplasms (Cancer)

4/2024	Comparative Preclinical Evaluation of HYNIC-Modified Designed Ankyrin Repeat Proteins G3 for the 99mTc-Based Imaging of HER2-Expressing Malignant Tumors.
12/2022	Direct In Vivo Comparison of 99mTc-Labeled Scaffold Proteins, DARPin G3 and ADAPT6, for Visualization of HER2 Expression and Monitoring of Early Response for Trastuzumab Therapy.
11/2022	Comparative Preclinical Evaluation of Peptide-Based Chelators for the Labeling of DARPin G3 with 99mTc for Radionuclide Imaging of HER2 Expression in Cancer.
9/2022	Novel Small Multilamellar Liposomes Containing Large Quantities of Peptide Nucleic Acid Selectively Kill Breast Cancer Cells.
1/2022	Phase I Trial of 99mTc-(HE)3-G3, a DARPin-Based Probe for Imaging of HER2 Expression in Breast Cancer.
11/2021	Barnase-Barstar Pair: Contemporary Application in Cancer Research and Nanotechnology.
5/2021	Natural and Designed Toxins for Precise Therapy: Modern Approaches in Experimental Oncology.
10/2020	Dual Targeting of Cancer Cells with DARPin-Based Toxins for Overcoming Tumor Escape.
5/2020	RNA Sequencing-Based Identification of Ganglioside GD2-Positive Cancer Phenotype.
5/2020	Feasibility of Imaging EpCAM Expression in Ovarian Cancer Using Radiolabeled DARPin Ec1.

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Sergey Deyev Research Topics

Disease

23	Neoplasms (Cancer) 04/2024 - 10/2015
7	Breast Neoplasms (Breast Cancer) 03/2024 - 10/2016
3	Ovarian Neoplasms (Ovarian Cancer) 11/2022 - 05/2019
3	Carcinoma (Carcinomatosis) 05/2020 - 10/2015
2	Adenocarcinoma 09/2019 - 05/2019
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 03/2024
1	B-Cell Leukemia (Leukemia, B Cell) 11/2021
1	Neoplasm Metastasis (Metastasis) 10/2020
1	Triple Negative Breast Neoplasms 10/2020
1	Lymphoma (Lymphomas) 05/2020
1	Disease Progression 06/2019
1	Multiple Sclerosis 07/2016

Drug/Important Bio-Agent (IBA)

16	Designed Ankyrin Repeat ProteinsIBA 04/2024 - 10/2016
6	Proteins (Proteins, Gene)FDA Link 06/2023 - 09/2018
5	Radioisotopes (Radionuclides)IBA 11/2022 - 01/2018
4	Liposomes (Liposome)IBA 09/2022 - 09/2018
4	human ERBB2 proteinIBA 09/2022 - 01/2018
4	Immunotoxins (Immunotoxin)IBA 01/2020 - 10/2015
3	ErbB Receptors (EGF Receptor)IBA 11/2022 - 10/2017
3	Epithelial Cell Adhesion MoleculeIBA 10/2020 - 05/2020
2	Chelating AgentsIBA 04/2024 - 11/2022
2	Lapatinib (GW572016)FDA Link 03/2024 - 01/2018
2	Trastuzumab (Herceptin)FDA Link 12/2022 - 01/2018
2	Bacillus amyloliquefaciens ribonucleaseIBA 11/2021 - 10/2020
2	GoldIBA 09/2019 - 10/2017
1	Amino Acids FDA Link 04/2024
1	glycyl-glycyl-glycine (triglycine)IBA 04/2024
1	glutamyl-glutamic acid (Glu-Glu)IBA 04/2024
1	Peptides (Polypeptides)IBA 11/2022
1	Peptide Nucleic AcidsIBA 09/2022
1	Bacillus amyloliquefaciens barstar protein (barstar)IBA 11/2021
1	Drug CarriersIBA 05/2021
1	PolymersIBA 05/2021
1	AntigensIBA 10/2020
1	GD2 gangliosideIBA 05/2020
1	EnzymesIBA 05/2020
1	GangliosidesIBA 05/2020
1	RNA (Ribonucleic Acid)IBA 05/2020
1	Telomerase (Telomerase Reverse Transcriptase)IBA 01/2020
1	DNA (Deoxyribonucleic Acid)IBA 01/2020
1	PolyethyleneimineIBA 01/2020
1	Doxorubicin (Adriamycin)FDA LinkGeneric 05/2019
1	Antineoplastic Agents (Antineoplastics)IBA 05/2019
1	Epidermal Growth Factor (EGF)IBA 01/2019
1	pertuzumabIBA 01/2018
1	Immunoconjugates (Immunoconjugate)IBA 01/2018
1	Technetium (Technetium 99m)IBA 01/2018
1	AntibodiesIBA 01/2018
1	Biomarkers (Surrogate Marker)IBA 01/2018
1	Ado-Trastuzumab EmtansineIBA 01/2018
1	Tyrosine Kinase InhibitorsIBA 01/2018
1	Pseudomonas aeruginosa Exotoxin AIBA 10/2016
1	Cytotoxins (Cytolysins)IBA 10/2016
1	Myelin-Oligodendrocyte GlycoproteinIBA 07/2016
1	AutoantigensIBA 07/2016
1	ExotoxinsIBA 10/2015

Therapy/Procedure

17	Therapeutics 04/2024 - 10/2017
1	Immunotherapy 05/2020
1	Injections 01/2020
1	Phototherapy (Light Therapy) 09/2019
1	Drug Therapy (Chemotherapy) 05/2019
1	Intravenous Administration 10/2016